HUGRO® Growth Factor Technology

Every drop of HUGRO® Peptide represents the culmination of 30 years of Korean biotechnology innovation. Unlike conventional skincare ingredients that treat only the surface, HUGRO® peptides are bioengineered recombinant growth factors that awaken the skin’s natural healing system and stimulate cellular skin regeneration.

Through a proprietary synthesis process combining Recombinant DNA Engineering, AUT (Anti-Ubiquitination Technology), and BMTS (Bio-Material Transdermal System), BioPlus USA created the first cell booster complex that can penetrate, survive, and remain active deep within the skin. This is not cosmetic enhancement — it is cellular regeneration.

What Makes HUGRO® Peptide Different

Recombinant Growth Factor Precision

Each HUGRO® peptide is replicated from the exact genetic sequence of human growth factors using recombinant DNA technology. This ensures bio-identical structure, purity, and clinical-grade stability — minimizing immune response and maximizing compatibility with human tissue.

AUT (Anti-Ubiquitination Technology)

In the body, active proteins are quickly degraded by ubiquitin. AUT blocks this process, extending the peptide’s half-life and allowing growth factors to remain active longer — up to 3x greater intracellular stability compared to conventional formulas.

BMTS (Bio-Material Transdermal System)

BMTS enables the peptide to pass through the cell membrane without damage, delivering growth factors directly into dermal cells. Clinical data shows over 90% absorption efficiency and deep penetration of 0.3–0.4 mm — the optimal range for fibroblast stimulation and collagen induction.

Clinical-Grade Performance

Independent studies show measurable improvements in skin density (+30%), wrinkle reduction (–17%), and scalp redness (–45%), while supporting biostimulator-driven skin regeneration after regular professional use.

HUGRO® Peptide Line-Up

Intelligent, Deep, and Long-Lasting Regeneration

HUGRO® Peptide is the core engine behind every BioPlus USA product — from Shine Plus Aura to Bonyx and Hair LC Aura Hair. It delivers real, visible transformation through cell-to-cell delivery, initiating regeneration that continues long after treatment.

Science doesn’t just touch the skin — it transforms it from within.

Experience HUGRO®

The Future of Cell-Based Aesthetic Science.

Partner with BioPlus USA and discover how recombinant peptide technology can redefine results through growth factor skin regeneration technology for your patients and your practice.