Pioneering Growth Factor Biotechnology

From Korea’s Biotechnology to America’s Medical Aesthetics Frontier

The Genesis of BioPlus

Founded on a vision to merge biotechnology and beauty, BioPlus began its journey in South Korea in the early 1990s as a research-driven life science company. Over decades of innovation, the company evolved from a biomedical materials manufacturer into a global leader in medical aesthetics — developing clinically tested skin boosters, fillers, and regenerative solutions that redefine how beauty and science can coexist.

The Timeline

30 years of biomedical innovation—from research roots to global expansion with BioPlus USA.

1992

Foundation (Started as a Research-driven Life Science Company)

2010

Biotech Transition (Focus shift to Biomedical Materials)

2020

HUGRO Launch (Breakthrough in Growth-Factor Technology)

2025

BioPlus USA Established (American Headquarters & Global Expansion)

Our Scientific Foundation

By pioneering technologies, BioPlus set new standards for cellular rejuvenation.

AUT (Anti-Ubiquitination Technology)

A specialized protein stabilization technology ensuring longer-lasting effects.

BMTS (Bio-Material Transdermal System)

Advanced delivery system allowing active ingredients to penetrate deep into the dermis.

HUGRO Platform

Proprietary recombinant growth-factor platform enabling true cell-level recovery and regeneration. (2020 Launch)

World-Class R&D Center & Manufacturing

Strict quality control and cutting-edge facilities in South Korea ensuring the highest purity and safety standards.

Empowering the Future of Aesthetics

In 2025, BioPlus USA was established to expand this biotechnological legacy. Today, we continue the mission to empower clinics, practitioners, and medical spas across the U.S. with next-generation skin regeneration and regenerative aesthetic treatments for clinics and medical spas.