Beyond Ingredients — A Revolution in Cellular Biotechnology
Every drop of HUGRO® Peptide represents the culmination of 30 years of Korean biotechnology innovation.
Unlike conventional skincare ingredients that treat only the surface, HUGRO® peptides are bioengineered recombinant growth factors that awaken the skin’s natural healing system at the cellular level.
Through a proprietary synthesis process combining Recombinant DNA Engineering, AUT (Anti-Ubiquitination Technology), and BMTS (Bio-Material Transdermal System), BioPlus USA created the first cell booster complex that can penetrate, survive, and remain active deep within the skin.
This is not cosmetic enhancement — it is cellular regeneration.
What Makes HUGRO® Peptide Different
Recombinant Growth Factor Precision
Each HUGRO® peptide is replicated from the exact genetic sequence of human growth factors using recombinant DNA technology. This ensures bio-identical structure, purity, and clinical-grade stability — minimizing immune response and maximizing compatibility with human tissue.
AUT (Anti-Ubiquitination Technology)
In the body, active proteins are quickly degraded by ubiquitin. AUT blocks this process, extending the peptide’s half-life and allowing growth factors to remain active longer — up to 3x greater intracellular stability compared to conventional formulas.
BMTS (Bio-Material Transdermal System)
BMTS enables the peptide to pass through the cell membrane without damage, delivering growth factors directly into dermal cells. Clinical data shows over 90% absorption efficiency and deep penetration of 0.3–0.4 mm — the optimal range for fibroblast stimulation and collagen induction.
Clinical-Grade Performance
Independent studies show measurable improvements in skin density (+30 %), wrinkle reduction (–17 %), and scalp redness (–45 %) after regular professional use.
HUGRO® Peptide Line-Up
Category |
Core Function |
Key Peptides & Growth Factors |
|---|---|---|
HUGRO® Peptide Human-Derived Growth Factors
|
Skin regeneration, elasticity, wound healing
|
EGF, FGF-1, KGF, IGF-1, PDGF AA/BB, TGF β2, TIMP-1, AP, VEGF, SCF
|
HUGRO® Peptide Protein Complex
|
Firmness and structure repair
|
Collagen, NOG (follicle and tissue homeostasis)
|
HUGRO® Peptide Analog
|
Advanced anti-wrinkle activity
|
LC BTX (Light-Chain Botulinum Peptide)
|
HUGRO® Peptide Enzyme / Hormone
|
Antioxidant protection and cell metabolism
|
SOD1, ALDH2, Growth Hormone
|
HUGRO® Peptide Complex (THE;ST Line)
|
Region-specific formulation
|
Hugro-W (Whitening), Hugro-F (Firming), Hugro-N (Neck), Hugro-H (Hair), etc.
|
Intelligent, Deep, and Long-Lasting Regeneration
HUGRO® Peptide is the core engine behind every BioPlus USA product — from Shine Plus Aura to Bonyx and Hair LC Aura Hair. It delivers real, visible transformation through cell-to-cell delivery, initiating regeneration that continues long after treatment.
Science doesn’t just touch the skin — it transforms it from within.
The Future of Cell-Based Aesthetic Science.
Partner with BioPlus USA and discover how recombinant peptide technology can redefine results for your patients and your practice.